EpiCom

An implementation of chemical-based mechanism enrichment with NeuroMMSig described by [Hoyt2018].

This algorithm has multiple steps:

  1. Select NeuroMMSig networks for AD, PD, and epilepsy
  2. Select drugs from DrugBank, and their targets
  3. Run NeuroMMSig algorithm on target list for each network and each mechanism
  4. Store in database
[Hoyt2018]Hoyt, C. T., et al. (2018) A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities, Database, Volume 2018, 1 January 2018, bay050
pybel_tools.analysis.epicom.multi_run_epicom(graphs, path)[source]

Run EpiCom analysis on many graphs.

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